The frequency of CCR5 promoter polymorphisms and CCR5 32 mutation in Iranian populations
Evidence showed that chemokines serve as pro-migratory factors for immune cells.CCL3, CCL4 and CCL5, as the main CC chemokines subfamily members, activate immune cells through binding to CC chemokine receptor 5 or CCR5.Macrophages, NK cells and T lymphocytes express CCR5 and thus, affected CCR5 expression or functions could be associated with alter